By Stanley Morison
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Extra resources for Les premiers principes de la typographie
G. ). htm. 36 Effexor will tell you how to obtain this information later in the chapter. The following is an example of the type of information that you can expect to obtain from a patent search on Effexor: • Derivatives of (+)-venlafaxine and methods of preparing and using the same Inventor(s): Senanayake; Chrisantha H. (Shrewsbury, MA), Jerussi; Thomas P. (Framingham, MA) Assignee(s): Sepracor, Inc. (Marlborough, MA) Patent Number: 6,197,828 Date filed: November 30, 1999 Abstract: Methods of preparing, and compositions comprising, derivatives of (+)venlafaxine are disclosed.
M. O. Box 221200; Chantilly; VA; 20153-1200; US Patent Application Number: 20030190352 Date filed: March 27, 2003 Abstract: Solid venlafaxine base can be advantageously employed in making pharmaceutical compositions, especially extended release compositions. S. provisional application 60/367,736, filed Mar. 28, 2002, the entire contents of which are incorporated herein by reference. The present invention relates to pharmaceutical compositions using venlafaxine base, to pharmaceutically useful forms of venlafaxine base and methods of making and using the same.
Pat. No. 4,761,501 and Pento, J. T. Drugs of the Future 13(9):839-840 (1988). RTM. , which is a racemic mixture of the (+) and (-) enantiomers of venlafaxine, is indicated for the treatment of depression. Klamerus, K. J. et al. J. Clin. Pharmacol. 32:716-724 (1992). All of these metabolites are racemic. In vitro studies suggest that O-desmethylvenlafaxine is a more potent inhibitor of norepinephrine and dopamine uptake than the parent compound racemic venlafaxine. Muth, E. A. et al. Drug Develop.