Extreme cold : a prevention guide to promote your personal by Centers for Disease Control and Prevention (U.S.)

By Centers for Disease Control and Prevention (U.S.)

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Extra info for Extreme cold : a prevention guide to promote your personal health and safety

Example text

Watson et al. (1980) found that lead absorption was two to three times greater for subjects with low iron stores than for subjects with high iron stores, as determined by serum ferritin levels. Flanagan et al. (1978) reported an inverse relationship between cadmium absorption and iron stores of human volunteers. 3% for 12 subjects with normal iron stores (serum ferritin less than 20 ng/ml for the low iron group, greater than 23 ng/ml for the normal group). Zinc In animal studies, decreased zinc status also contributes to lead and cadmium toxicity.

This situation justifies a problem analysis applying models used in pediatric nutrition (Fomon, 1967). Although reliable data of heavy metal accumulation during childhood are still missing, lead appears to be the element that has been explored more than cadmium and mercury so far. Therefore, lead data are being utilized for the more general considerations to follow. Table 1 compiles some of the sources that have been used. In addition to annual intakes of energy and lead, in some instances, daily energy consumption as well as lead-intakes during specific age intervals have been utilized.

These two examples will, I think, illustrate that ADIs are not magic figures, and that their application requires something more than mere administrative skills. Provisional Tolerable Weekly Intakes In 1972, a new approach was adopted by the Joint FAO/WHO Expert Committee on Food Additives in dealing with metal contaminants in food: the concept of the "provisional tolerable weekly intake". The basis "for this approach was as follows: "(a) The contaminants are able to accumulate within the body at a rate and to an extent determined by the level of intake and by the chemical form of the heavy metal present in food.

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