Epilepsy Case Studies: Pearls for Patient Care by Elaine Wirrell M.D. (auth.), William O. Tatum, Joseph I.

By Elaine Wirrell M.D. (auth.), William O. Tatum, Joseph I. Sirven, Gregory D. Cascino (eds.)

Written by means of professional epilepsy clinicians from the Mayo health facility, Epilepsy Case stories: Pearls for sufferer Care offers a wide selection of case histories drawn from “real existence” stories in individuals with seizures. Designed to stimulate a similar deductive reasoning that's conventional while seeing epilepsy sufferers within the health center, this sensible ebook offers the scientific state of affairs after which poses a number of stimulating inquiries to set up the reader’s strategies to handle each one case. Questions that revolve round each one case comprise universal ones comparable to “How does this try support us with the diagnosis?” and “What is definitely the right courting of the patient’s seizures to their total neurological condition?” the main poignant questions comprise “How does this data aid us to plan a remedy plan?” and “What can we learn about the predicted direction and prognosis?” The questions raised in every one part comprise the medical path and review. the place attainable, the dialogue depends the newest scientific facts to aid the responses and comprises up to date suggestions used for sufferers with and with no seizure keep watch over. on the finish of every case a couple of salient citations are referenced, as are many of the extra pertinent articles that the reader can connection with receive an outline of the subject. Take-home messages are encapsulated within the kind of scientific pearls which are designed to shape the fundamental figuring out of the case eventualities offered. a tremendous contribution to the literature in epileptology, Epilepsy Case reviews: Pearls for sufferer Care will be a useful reference for all clinicians who deal with sufferers with epilepsy.

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Diazepam rectal gel) in the case of serial (“cluster”) seizures. They should understand that they do not need to go to the emergency department (ED) with every seizure, but that injury, persistent seizures, cardiorespiratory compromise, and failure to recover after a seizure should direct physician assessment. Seizure counts to quantify the number of different seizure types are a helpful attempt to reflect the degree of changes in seizure frequency. Epileptic spasms (West’s syndrome) may precede LGS with adrenocorticotropic hormone (ACTH) “shots” in 40 %.

Lamotrigine appears to have less adverse effects, but is less effective than VPA or Ethosuximide (ETH). ETH appears to be the best choice of ASDs when treating absence seizures. This is due to the optimal balance between efficacy and adverse effects. Drugs, such as ETH, that are effective in controlling absence seizures affect the T-type calcium currents. The most frequent adverse effects of ETH are gastric irritation. This can often be controlled by taking it after eating rather than on an empty stomach.

A routine EEG (Fig. 1) revealed the following: Clinical Questions 1. 2. 3. 4. 5. How does the EEG help support the clinical history for a diagnosis? What should the family know about this condition? What other conditions may mimic this case presentation? What is the best course of treatment? What is the anticipated prognosis? 5 Lennox–Gastaut Syndrome 23 Diagnostic Discussion 1. The EEG demonstrates generalized slow-spike-waves. This is one of the characteristic features of the electroclinical syndrome of LGS.

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