Fibrosis - A Medical Dictionary, Bibliography, and Annotated by Health Publica Icon Health Publications

By Health Publica Icon Health Publications

It is a 3-in-1 reference ebook. It offers an entire scientific dictionary overlaying thousands of phrases and expressions with regards to fibrosis. It additionally supplies wide lists of bibliographic citations. ultimately, it presents details to clients on easy methods to replace their wisdom utilizing quite a few web assets. The ebook is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with study devoted to fibrosis. in case your time is effective, this ebook is for you. First, you won't waste time looking out the web whereas lacking loads of proper details. moment, the ebook additionally saves you time indexing and defining entries. ultimately, you won't waste time and cash printing hundreds of thousands of web content.

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Extra info for Fibrosis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

Example text

Mice deficient in avB6 lack the ability to activate local TGFbeta through this alphavbeta6 integrin dependent mechanism and had marked protection against fibrosis in the unilateral ureteral obstruction model, with decreased PAI-1 expression, despite robust infiltration of macrophages. A full fibrotic response was restored by infusion of angiotensin or aldosterone, together with restoration of local increase of PAI-1. These projects will examine the TGFbeta1 dependent and independent mechanisms of fibrosis.

The importance of the work relates to the large numbers of asbestos and silica exposed individuals, and to the continual exposure of the public to potentially fibrogenic particles in the urban environment. By improving understanding of these mechanisms, this work may allow development of improved therapies. ; Professor; Vanderbilt University 3319 West End Ave. Nashville, Tn 372036917 Timing: Fiscal Year 2002; Project Start 01-APR-1992; Project End 31-MAR-2007 Summary: Description (provided by applicant) Transforming growth factor-beta 1 (TGFbeta) has been implicated as a key molecule in fibrosis, and its expression is increased in numerous fibrotic conditions.

Medicine; Mount Sinai School of Medicine of Nyu of New York University New York, Ny 10029 Timing: Fiscal Year 2002; Project Start 15-FEB-2002; Project End 31-JAN-2007 Summary: (provided by applicant) Understanding mechanisms that favor regenerative rather than fibrotic responses is essential to developing strategies for treating and reversing chronic liver disease. This application addresses the central role played by interleukin-6 (IL-6) in determining this outcome through its effects on the activity of matrix degrading proteases in liver.

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