Ciba Foundation Symposium - Ageing in Transient Tissues

Chapter 1 Chairman's establishing comments (pages 1–2): E. C. Amoroso
Chapter 2 Organ tradition reports of Foetal Rat Reproductive Tracts (pages 3–17): Dorothy cost and Richard Pannabecker
Chapter three The Age think about a few Prenatal Endocrine occasions (pages 18–30): Alfred Jost
Chapter four The Regenerative means of Ovarian Tissue (pages 31–58): S. Zuckerman
Chapter five The heritage and destiny of Redundant Follicles (pages 59–68): P. C. Williams
Chapter 6 The Corpus Luteum of the Guinea Pig (pages 69–85): I. W. Rowlands
Chapter 7 Observations at the Cytomorphosis of the Germinal and Interstitial Cells of the Human Testis (pages 86–99): Don W. Fawcett and Mario H. Burgos
Chapter eight Mitochondrial alterations in several Physiological States (pages 100–104): Edward W. Dempsey
Chapter nine Morphological elements of getting old within the Placenta (pages 105–117): George B. Wislocki
Chapter 10 Chronological adjustments in Placental functionality (pages 118–128): A. St. G. Huggett
Chapter eleven Biochemical proof of getting older within the Placenta (pages 129–147): Claude A. Villee
Chapter 12 Uptake of Radio?Potassium (42K) by means of the Uterus and Placenta throughout the development of being pregnant within the Rat and the Goat (pages 148–160): R. J. Harrison and J. L. D'Silva
Chapter thirteen changes within the Foetal improvement of the Rat After management of development Hormone or Cortisone to the mummy (pages 161–175): Herbert Tuchmann?Duplessis and Lucette Mercier?Parot
Chapter 14 the expansion Cycle of Deer Antlers (pages 176–187): George B. Wislocki
Chapter 15 growing older of the Axillary Apocrine Sweat Glands within the Human woman (pages 188–201): William Montagna
Chapter sixteen The Metabolism of Senescent Leaves (pages 202–214): E. W. Yemm
Chapter 17 The actual Instability of Human pink Blood Cells and its attainable significance of their Senescence (pages 215–232): J. E. Lovelock
Chapter 18 getting old in Human crimson Cells (pages 233–256): P. L. Mollison

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Mature guinea pig. Nest of oocytes showing phases of meiosis, including apparent zygotens. 4. Old guinea pig. Nest of oocytes showing phases of meiosis, including apparent zygotene. 5. Normal oocyte, showing pachytene phase of meiosis. 6. Three stages of meiosis. facing page 41 REGENERATIVE CAPACITY OF OVARIAN TISSUE 41 which Aron and his collaborators now report in the guinea pig, and which we can confirm from personal observation. One often finds in the ovarian cortex of this animal, cells, frequently crowded together in nests, which seem t o be either oogonia or oocytes.

Right ovary removed: left ovary untreated. C. same as A, but remaining fragment of left ovary painted with tannic acid in order t o destroy the germinal epithelium. D. right ovary removed: surface of whole left ovary painted with tannic acid. Compensatory hypertrophy occurred in the ovarian tissue left in the body, whether or not the germinal epithelium was present, and was not associated with any increase in the expected number of oocytes. At the same time a unilaterallyovariectomized animal lost fewer oocytes within a given period than a normal animal possessing both ovaries.

During the short period of time involved, the testis has completely changed the properties of a special part of the urogenital sinus, which has become the prostatic region. It would be of great importance t o know what happened in these cells, what kind of change they underwent. After day twenty-four the male rabbit foetus is definitely marked as a male ;the sexual structures have passed a turningpoint after which removal of the testis does not inhibit further differentiation. Even if the testicular function of the normal male were reduced at late stages of pregnancy, the sexual organogenesis would be normal : something similar seems t o happen in the human foetus, in which the testicular intestitial cells are very large and rich in cytoplasm from the stage of 8 cm.

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